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1994-09-03
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Document 0056
DOCN M9490056
TI HIV-1 seroprevalence in an inner-city public hospital.
DT 9411
AU Nagachinta T; Brown CP; Cheng F; Temple W; Kerndt PR; Janssen RS;
Division of HIV/AIDS, Centers for Disease Control and Prevention,;
Atlanta, GA.
SO J Natl Med Assoc. 1994 May;86(5):358-62. Unique Identifier : AIDSLINE
MED/94322400
AB In a hospital-based seroprevalence survey for human immunodeficiency
virus type 1 (HIV-1) infection, a stratified sampling method based on
age and gender was used to collect 5429 blood samples at an inner-city
hospital. Sentinel Hospital Surveillance System (SHSS) criteria
developed by the Centers for Disease Control and Prevention were used to
classify patient diagnoses into two categories by the likelihood of
being associated with HIV-1 infection. The two categories were those
with high likelihood of association with HIV-1 (SHSS-ineligible) and
those with low likelihood of association with HIV-1 infection
(SHSS-eligible). Of the 5429 blood samples, 4262 were SHSS-eligible and
1167 were SHSS-ineligible. After personal identifies were removed,
specimens were tested by ELISA and confirmed by Western blot analysis.
The overall prevalence rate of HIV-1 infection was 0.98%. The
seroprevalence rate was almost 2.6 times higher in high-association
patients compared with low-association patients (1.89% versus 0.73%, P <
.001). Results from this study indicate a high unsuspected HIV-1
seroprevalence rate in a subpopulation (SHSS-eligible) considered to
have diagnoses with low likelihood of association with HIV-1 infection.
These patients may better approximate HIV-1 seroprevalence in the
general population of the area served by the hospital than would a
sample of all patients. Monitoring HIV-1 seroprevalence in the
SHSS-eligible group will be a useful measure for community
serosurveillance for HIV-1 infection.
DE Acquired Immunodeficiency Syndrome/DIAGNOSIS/*EPIDEMIOLOGY Adolescence
Adult Age Factors Aged Child Child, Preschool Comparative Study
Ethnic Groups/*STATISTICS & NUMER DATA Female Hospitals, Public
Hospitals, Urban/*UTILIZATION Human *HIV Seroprevalence Infant
Infant, Newborn Male Middle Age Pilot Projects Prevalence Sex
Factors Support, U.S. Gov't, P.H.S. United States JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).